Sumários
Hands-on project: non-viral vectors
27 março 2019, 16:30 • Gabriel Monteiro
Hands-on project: non-viral vectors. (project implemented and performed by students)
Manufacturing of non-viral vectors
15 março 2019, 15:00 • Duarte Miguel de França Teixeira dos Prazeres
Manufacturing of non-viral vectors. Product and process development. Regulation framework and the quality tripod (GLPs, GMPs and GCPs). INDs and BLAs. Clinical trials. Quizz on clicnial trials an regulation. Overview of plasmid manufacturing. Main impurities and key properties: genomic DNA, RNA, LPS and RNA. In-class group exercise on test items, specifications and analytics.
Gene therapy by the numbers
13 março 2019, 16:30 • Duarte Miguel de França Teixeira dos Prazeres
Gene therapy by the numbers. A quantitative approach to cell biology. Key numbers in Biology: size, length scale, concentration, diffusion. Basic calculations and estimates.