Fighting Cancer Challenge - Presentations by the students

31 Maio 2019, 15:00 Cláudia Lobato da Silva

Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma
83742 Adriana Passadouro

83757 Carlos Clara
83808 Ana Lúcia Tiago
83835 Madalena Theriaga
93956 David Alves

Inducible Caspase9-mediated suicide gene for MSC-based cancer
81037 Miguel Alves
83764 Eduardo Gameiro
83791 Marta Avelar
83793 Marta Costa
90912 Ricardo Brancal

Targeted delivery of doxorubicin by nano-loaded mesenchymal stem cells for lung melanoma metastases therapy
83848 Marta Oliveira
83852 Pedro Batalha
83857 Sofia Cotrim
94556 Luciana De Cesare
94575 Martin Mandelbaum

Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer
80836 Luís Coutinho
92042 Anna Aadnoey
93923 Gonçalo Fernandes
93957 Marta Patinha
93970 Pedro Coelho
94022 Joana Diogo

microRNA‐16‐5p‐containing exosomes derived from bone marrow‐derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting apoptosis of colorectal cancer cells by downregulating ITGA2
83376 Inês Duarte
91924 Léa Dac
94418 Honorine Vellenriter
94433 Ida Isacsson

Ethics in Stem Cell Research

29 Maio 2019, 16:30 Cláudia Lobato da Silva

Ethics in human embryonic stem cell research.

Ethics in clinical trials exploiting new cellular therapies. Stem Cell Tourism.
Case studies.


24 Maio 2019, 15:00 Duarte Miguel de França Teixeira dos Prazeres

Bioethics. Who is involved and why we care about Bioethics. Examples of Bioethics dilemas: Gene therapy, Cloniing, OGMs, Animal testing, Stem cells, Tissue ownership, Genetic testing, Gene enhancement, Euthanasia, Biopiracy, organ transplant, etc. Case study: John Moore, the $3 billion man.


22 Maio 2019, 16:30 Gabriel António Amaro Monteiro

Bioethics – Gene manipulation and gene therapy. Case studies

Cellular/Gene Therapy for Cancer

17 Maio 2019, 15:00 Cláudia Lobato da Silva

Cancer and therapeutic strategies. Immunotherapy. Stem cell-based therapies to fight cancer.

Hands-on project: Engineering stem cells to fight cancer.The students were organized in 5 groups. Each group selected a recent, non-review paper related to one of the topics (one topic per group):
1) Genetic engineering of stem cells to secrete anticancer proteins
2) Genetic engineering of stem cells to induce cancer cell death
3) Stem cells as nanoparticle carriers
4) Stem cells loaded with oncolytic virus
5) Exosomes