Sumários
Metabolic pathway modeling
3 maio 2019, 13:30 • Miguel Nobre Parreira Cacho Teixeira
Metabolic pathway modeling using the COPASI software. Mathematical description of biochemical pathways. Simulation of pathway behavior upon changes in enzyme kinetic parameters and upon changes in substrate concentrations.
Introduction to Systems Biology
2 maio 2019, 10:00 • Miguel Nobre Parreira Cacho Teixeira
Introduction to Systems Biology. Definition and goals of this new discipline. Mathematical modeling of biochemical and regulatory pathways: general concepts, constraints and assets. Genomic Scale Models. Sctoichiometric matrix. Fluxome analysis.
Metabolic pathway modeling
30 abril 2019, 15:30 • Miguel Nobre Parreira Cacho Teixeira
Metabolic pathway modeling using the COPASI software. Mathematical description of biochemical pathways. Simulation of pathway behavior upon changes in enzyme kinetic parameters and upon changes in substrate concentrations.
Functional Genomics (cont.)
30 abril 2019, 09:00 • Miguel Nobre Parreira Cacho Teixeira
Omics approaches for the study of protein-protein (genome-wide yeast two-hybrid system; protein chips), protein-DNA (ChIP-on-chip and ChIP-seq) and protein-ligand (protein chips) interactions.
Genome-wide data analysis using bioinformatics tools
26 abril 2019, 13:30 • Miguel Nobre Parreira Cacho Teixeira
Integrated transcriptome and disruptome data analysis using bioinformatics tools: GOToolBox, KEGG, YEASTRACT and STRING. The propionic acid case-study.