Selected publications D. Ramalho, P. Constantino, H. P. D. Silva, M. Constante and J. Sanches, "An Augmented Teleconsultation Platform for Depressive Disorders," in IEEE Access, vol. 10, pp. 130563-130571, 2022, doi: 10.1109/ACCESS.2022.3228324. Hemaxi Narotamo, Sofia Fernandes, Ana Margarida Moreira Soraia Melo, Raquel Seruca, Margarida Silveira and J. Miguel Sanches, A machine learning approach for single cell interphase cell cycle staging . Sci Rep 11, 19278 (2021). https://doi.org/10.1038/s41598-021-98489-5 Figueiredo J, Rodrigues I, Ribeiro J, Fernandes MS, Melo S, Sousa B, Paredes J, Seruca R, Sanches JM, Geometric compensation applied to image analysis of cell populations with morphological variability: a new role for a classical concept , Scientific Reports (Nature), 2018 Jul 6;8(1):10266. doi: 10.1038/s41598-018-28570-z. Anabela Ferro, Tânia Mestre, Patrícia Carneiro, Ivan Sahumbaiev, Raquel Seruca and João M. Sanches, Blue intensity matters for cell cycle profiling in fluorescence DAPI-stained images , Laboratory Investigation (Nature), 6 March 2017. doi:10.1038/labinvest.2017.13. Mestre T, Figueiredo J, Ribeiro AS, Paredes J, Seruca R and Sanches JM, Quantification of topological features in cell meshes to explore E-cadherin dysfunction, Scientific Reports (Nature). 2016 May 6;6:25101 , doi: 10.1038/srep25101. Afonso, M.V.; Miguel Sanches, J., Blind Inpainting using L0 and Total Variation Regularization , Image Processing, IEEE Transactions on , Vol. 24, No. 7, July 2015, doi: 10.1109/TIP.2015.2417505 (URL ). Domingues, A; Paiva, T.; Sanches, J.M., Hypnogram and Sleep Parameter Computation From Activity and Cardiovascular Data , Biomedical Engineering, IEEE Transactions on , vol.61, no.6, pp.1711,1719, June 2014, doi: 10.1109/TBME.2014.2301462. Seabra, J.C.; Ciompi, F.; Pujol, O.; Mauri, J.; Radeva, P.; Sanches, J., Rayleigh Mixture Model for Plaque Characterization in Intravascular Ultrasound , Biomedical Engineering, IEEE Transactions on , vol.58, no.5, pp.1314-1324, May 2011. Isabel Rodrigues and João Sanches, Convex Total Variation Denoising of Poisson Fluorescence Confocal Images with anisotropic filtering , IEEE TRANSACTIONS ON IMAGE PROCESSING, VOL. 20, NO. 1, JANUARY 2011. Sanches, J. M. Nascimento, J. C.Marques, J.S.,Medical Image Noise Reduction Using the Sylvester–Lyapunov Equation , IEEE Transactions on Image Processing, Volume: 17, Issue: 9 , pp.1522-1539, September. 2008.