Sumários
Peptide synthesis
18 outubro 2022, 14:00 • Maria Matilde Soares Duarte Marques
Overview of strategies for peptide synthesis. Emphasis on solid state synthesis. Strategies to obtain long peptides (eg, stepwise elongations versus fragment condensation and chemical ligation). Synthesis of cyclic peptides.
Amino acids, peptides and proteins
13 outubro 2022, 14:00 • Maria Matilde Soares Duarte Marques
Properties of alpha-amino acids. Peptides and proteins. The four levels of protein structure and interactions involved in stabilizing secondary, tertiary and quaternary protein structures - examples. Agents that trigger protein denaturation.
Overview of fatty acids and lipids
11 outubro 2022, 14:00 • Maria Matilde Soares Duarte Marques
Fatty acids: characteristics and properties; omega-3 fatty acids; brief overview of fatty acid biosynthesis. General types of lipids - hydrolyzable (eg., triglycerides, phospholipids, and glycolipids) and non-hydrolyzable (e.g., steroids and bile acids). Lipid peroxidation. Biological relevance of lipids..
The 2022 Nobel prize in Chemistry
6 outubro 2022, 14:00 • Maria Matilde Soares Duarte Marques
Overview of the principles underlying the work that received the 2022 Nobel prize in Chemistry.
Brief overview of Coordination Chemistry. Introduction to bioinorganic chips and sensors.
4 outubro 2022, 14:00 • Maria Matilde Soares Duarte Marques
Review of the basic concepts of coordination chemistry. Applications. Coordination chemistry in biomolecules.