Motif Finding
26 outubro 2009, 12:30 • Sara Madeira
Finding Regulatory Motifs in DNA Sequences
- Background: Central Dogma in Molecular Biology. Transcription factor binding sites (TFBS). Gene Regulation.
- Motif Logo.
- Finding Motifs: Goals and problems.
- Motifs, profiles and consensus.
- Scoring motifs.
- Motif Finding Problem: Brute Force Algorithm (maximizing score vs minimizing distances).