Sumários
Metabolic pathway modeling
14 dezembro 2012, 11:00 • Miguel Nobre Parreira Cacho Teixeira
Metabolic pathway modeling using the COPASI software. Mathematical description of biochemical pathways. Simulation of pathway behavior upon changes in enzyme kinetic parameters and upon changes in substrate concentrations.
Metabolic pathway modeling
12 dezembro 2012, 12:30 • Miguel Nobre Parreira Cacho Teixeira
Metabolic pathway modeling using the COPASI software. Mathematical description of biochemical pathways. Simulation of pathway behavior upon changes in enzyme kinetic parameters and upon changes in substrate concentrations.
Introduction to Systems Biology (cont.)
12 dezembro 2012, 11:00 • Miguel Nobre Parreira Cacho Teixeira
Genomic Scale Models. Sctoichiometric matrix. Fluxome analysis.
Metabolomics data analysis
7 dezembro 2012, 11:00 • Miguel Nobre Parreira Cacho Teixeira
Metabolomics data analysis using the online tool MetaboAnalyst: statistical (Correlation analysis, PCA, PLS-DA and clustering) and pathway enrichment analysis. Biological interpretation of the data.
Introduction to Systems Biology
6 dezembro 2012, 08:00 • Miguel Nobre Parreira Cacho Teixeira
Introduction to Systems Biology. Definition and goals of this new discipline. Mathematical modeling of biochemical and regulatory pathways: general concepts, constraints and assets. The FLR1 regulatory network as a Systems Biology case-study.