Metabolomics analysis

2 maio 2017, 09:00 • Miguel Nobre Parreira Cacho Teixeira

Metabolomics: definition and principles. Critical analysis of sample preparation and metabolite extraction methods.Metabolomics analysis using MS approaches: GS-MS, LC-MS and DIMS. Metabolomics analysis based on NMR.Chemometrics approaches to NMR or MS data analysis: PCA and PLS-DA. Examples of application of metabolomics tools to the study of silent mutations, functional genomics and metabolic module definition.