Sumários

Seminar presentations by the students III

30 maio 2019, 14:00 Cláudia Lobato da Silva

Presentation of seminars by the following groups of students:

Beatriz Lopes Francisco Costa
Murdock MH, David S, Swinehart IT, Reing JE, Tran K, Gassei K, Orwig KE, Badylak SF. Human testis extracellular matrix enhances human spermatogonial stem cell survival in vitro. Tissue Eng Part A. 2018 Oct 12. doi: 10.1089/ten.TEA.2018.0147.

Umi Mir Kato and Marta Trullols de la Muela
Zhang Q, Nguyen PD, Shi S, Burrell JC, Cullen DK, Le AD. 3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration. Sci Rep. 2018 Apr 26;8(1):6634. doi: 10.1038/s41598-018-24888-w.

Joana Martins and Luís Coutinho
Shigemoto-Kuroda T, Oh JY, Kim DK, Jeong HJ, Park SY, Lee HJ, Park JW, Kim TW, An SY, Prockop DJ, Lee RH. MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis. Stem Cell Reports. 2017 May 9;8(5):1214-1225. doi: 10.1016/j.stemcr.2017.04.008.

Luciana De Cesare and Martin Mandelbaum
Ghaedi M, Le AV, Hatachi G, Beloiartsev A, Rocco K, Sivarapatna A, Mendez JJ, Baevova P, Dyal RN, Leiby KL, White ES, Niklason LE. Bioengineered lungs generated from human iPSCs-derived Epithelial Cells on Native Extracellular Matrix. J Tissue Eng Regen Med. 2017 Oct 12. doi: 10.1002/term.2589.Pedro 

Batalha and Marta Silva
Camp JG, Sekine K, Gerber T, Loeffler-Wirth H, Binder H, Gac M, Kanton S, Kageyama J, Damm G, Seehofer D, Belicova L, Bickle M, Barsacchi R, Okuda R, Yoshizawa E, Kimura M, Ayabe H, Taniguchi H, Takebe T, Treutlein B. Multilineage communication regulates human liver bud development from pluripotency. Nature. 2017 Jun 22;546(7659):533-538. doi: 10.1038/nature22796.


Seminar presentations by the students II

28 maio 2019, 13:30 Cláudia Lobato da Silva

Presentation of seminars by the following groups of students: 

Katarina Aamlid and Mimmi Håkansson
De Francesco EM, Bonuccelli G, Maggiolini M, Sotgia F, Lisanti MP. Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs). Oncotarget. 2017 Jun 9;8(40):67269-67286. doi: 10.18632/oncotarget.18428.

Jenna Suoranta and Laurenz Berger
Gao L, Kupfer ME, Jung JP, Yang L, Zhang P, Da Sie Y, Tran Q, Ajeti V, Freeman BT, Fast VG, Campagnola PJ, Ogle BM, Zhang J. Myocardial Tissue Engineering With Cells Derived From Human-Induced Pluripotent Stem Cells and a Native-Like, High-Resolution, 3-Dimensionally Printed Scaffold. Circ Res. 2017 Apr 14;120(8):1318-1325. doi: 10.1161/CIRCRESAHA.116.310277.

Federico Awruch and Clara Latour
Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S3, Quang D, Johnston S, Parylak SL, Jin X, Gage FH, An in vivo model of functional and vascularized human brain organoids, Nature Biotech. 2018 Jun;36(5):432-441. doi: 10.1038/nbt.4127. Epub 2018 Apr 16.


Seminar presentations by the students I

23 maio 2019, 14:00 Cláudia Lobato da Silva

 Presentation of seminars by the following groups of students: 


Sofia Navalho and Mariana Vassal Rodrigues 
AL, Rodrigues CAV, Gomes AR, Vieira SF, Badenes SM, Diogo MM, Cabral JMS. Dissolvable Microcarriers Allow Scalable Expansion And Harvesting Of Human Induced Pluripotent Stem Cells Under Xeno-Free Conditions. Biotechnol J. 2018 Oct 15:e1800461. doi: 10.1002/biot.201800461. [Epub ahead of print].

Ana Lúcia Tiago and Marta Oliveira
Kadota S, Pabon L, Reinecke H, Murry CE. In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts. Stem Cell Reports. 2017 Feb 14;8(2):278-289.

Ana Glória Cruz and Madalena Theriaga Gonçalves
Wang Y, Wang H, Deng P, Chen W, Guo Y, Tao T, Qin J. In situ differentiation and generation of functional liver organoids from human iPSCs in a 3D perfusable chip system. Lab Chip. 2018 Oct 25. doi: 10.1039/c8lc00869h.

Oda Oppedal and Sofia Cotrim
Jo J, Xiao Y, Sun AX, Cukuroglu E, Tran HD, Göke J, Tan ZY, Saw TY, Tan CP, Lokman H, Lee Y, Kim D, Ko HS, Kim SO, Park JH, Cho NJ, Hyde TM, Kleinman JE, Shin JH, Weinberger DR, Tan EK, Je HS, Ng HH. Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons. Cell Stem Cell, 2016, 19(2):248-57. doi: 10.1016/j.stem.2016.07.005.


Application of bioreactors for stem cell culture: Case studies.

21 maio 2019, 13:30 Cláudia Lobato da Silva

Invited Seminar by Doctor Carlos Rodrigues and Doctor Ana Fernandes (both from iBB/IST) on the application of bioreactors for expansion and controlled differentiation of human stem cells.


Bioreactors for Stem Cell Culture

16 maio 2019, 14:00 Cláudia Lobato da Silva

Bioreactor development for stem cell expansion and controlled differentiation.  Different culture formats: planar systems, microcarriers and cell aggregates.

Case studies: stem cells in tissue engineering versus cellular therapies.