T. Pinheiro, 13th International Conference on Microprobe Technology and Applications (ICNMTA2012) 2013;306:1-2. http://dx.doi.org/10.1016/S0168-583X(13)00525-9.

R.M. Godinho, J. Raimundo, C. Vale, B. Anes, P. Brito, L.C. Alves, T. Pinheiro. Micro-scale elemental partition in tissues of the aquatic plant Lemna minor L. exposed to highway drainage water. Nucl Instrum Methods B 2013;306: 150-152. 152   DOI: 10.1016/j.nimb.2012.10.032

T. Pinheiro, L. Moita, L. Silva, E. Mendonça, A. Picado. Nuclear microscopy as a tool in TiO2 nanoparticles bioaccumulation studies in aquatic species. Nucl Instrum Methods B 2013; 306:117-120. DOI: 10.1016/j.nimb.2012.12.049

S.M. Almeida, M.C. Freitas, M. Reis, T. Pinheiro, P.M. Felix, C.A. Pio. Fifteen Years of Nuclear Techniques Application to Suspended Particulate Matter Studies, The Journal of Radioanalytical and Nuclear Chemistry. 2013; 297(3):347-356. http://dx.doi.org/10.1007/s10967-012-2354-1.

M.A. Barreiros, T. Pinheiro, P.M. Felix, C. Franco, M. Santos, F. Araújo, M.C. Freitas, S.M. Almeida. Exhaled Breath Condensate as a biomonitor for metal exposure: A new analytical challenge. J. Radional Nucl Chem. J. Radional Nucl Chem. 2013;297-377-382. http://dx.doi.org/10.1007/s10967-012-2366-x

P.M. Félix, S.M. Almeida, T. Pinheiro, J. Sousa, C. Franco, H.Th. WolterbeekAssessment of exposure to metals in lead processing industries. Int J Environm Health. 2013; 216:17–24. doi:10.1016/j.ijheh.2012.03.003

P.M. Félix, C. Franco, M.A. Barreiros, B. Batista, S. Bernardes, S.M. Garcia, A.B. Almeida, S.M. Almeida, H.Th. Wolterbeek, T. Pinheiro. Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization. Archives of Environmental and Occupational Health. 2013; 68(2)72-79. http://dx.doi.org/10.1080/19338244.2011.638951.

M.D. Ynsa, R. Minquin, R. Rajendran, T. Pinheiro, F. Watt. Consequences of fat diet in the distribution of minerals within pancreatic tissues of rats and rabbits. Microscopy and Microanalysis 2012;18:1060–1066. http://dx.doi.org/10.1017/S1431927612001547.

I. Emerit, J. Antunes, J,M. Silva, J. Freitas, T. Pinheiro, P. Filipe. Clastogenic Plasma Factors in Psoriasis - Comparison of phototherapy and anti-TNFa treatments. Photochem Photobiol 2011; 87:1427-1432. DOI: 10.1111/j.1751-1097.2011.00982.x.

A.V. Silva, S.M. Almeida, M.C. Freitas, A.M. Marques, A.I. Silva, C.A. Ramos, T. Pinheiro. INAA and PIXE characterization of heavy metals and rare earth elements emissions from phosphorite handling in harbours. J Radioanal Nucl Chem 2012;294(2):277-281. DOI: 10.1007/s10967-011-1524-x.

M. Mota Carmo, P. Napoleão, S. Andrade, A.M. Selas, C. Freixo, A Turkman, V. Andreozzi, A.M. Viegas-Crespo, T. Pinheiro, R.C. Ferreira, High Oxidized LDL Associate to Low T-Lymphocytes in Acute Myocardial Infarction. Circulation 2010;122: E161.

S.M. Almeida, P.M. Félix, C. Franco, M.C. Freitas, L.C. Alves, T. Pinheiro, M.A. Barreiros, S.M. Garcia. Using the exhaled breath condensate as a tool non-invasive evaluation of pollutant exposure. Int. J. Environment and Health 2010;4:293-304.

P. Filipe, J.N. Silva, R. Silva, J.L. Cirne de Castro, M. Marques Gomes, L.C. Alves, R. Santus, T. Pinheiro, Stratum Corneum Is an Effective Barrier to TiO2 and ZnO Nanoparticle Percutaneous Absorption, Skin Pharmacol Physiol 2009;22:266-75. doi: 10.1159/000235554

I. Gomez-Morilla, T. Pinheiro, S. Odenbach, M.D. Ynsa Alcala, X-ray tomography as a complementary technique to Nuclear Microscopy for biomedical applications. Nucl Instrum Meth 2009;267:2103-2106.

E. Gontier;  M.D. Ynsa;  T. Bíró;  J. Hunyadi;  B. Kiss;  K. Gáspár;  T. Pinheiro;  J.N. Silva;  P. Filipe;  J. Stachura;  W. Dabros;  T. Reinert;  T. Butz;  P. Moretto; J.E. Surléve-Bazeille. Is there penetration of titania nanoparticles in sunscreens through skin? A comparative electron and ion microscopy study. Nanotoxicology 2008;2:218 – 231. http://dx.doi.org/10.1080/17435390802538508.


C.C. Marques, S.I. Gabriel, T. Pinheiro, A.M. Viegas-Crespo, M.L. Mathias, M.J. Bebianno. Metallothionein levels in Algerian mice (Mus spretus) exposed to elemental pollution: an ecophysiological approach. Chemosphere 2008;71:1340-1347.

T. Mrak, J. Simčič, P. Pelicon, Z. Jeran, M.A. Reis, T. Pinheiro. Use of micro-PIXE in the study of arsenate uptake in lichens and its influence on element distribution and concentrations. Nucl. Instrum. Meth. 2007; 260:245-253. doi:10.1016/j.nimb.2007.02.029

T. Pinheiro, J.Pallon, L.C. Alves, A. Veríssimo, P. Filipe, J.N. Silva, R. Silva. The influence of corneocyte structure on the interpretation of permeation profiles of nanoparticles across skin. Nucl. Instrum. Meth. 2007; 260:119-123.

A. Veríssimo, L.C. Alves, P. Filipe, J.N. Silva, R. Silva, M.D. Ynsa, E. Gontier, Ph. Moretto, J. Pallon, T. Pinheiro. Nuclear Microscopy: a tool for imaging elemental distribution and percutaneous absorption in vivo. Microscopy Res Tech 2007;70:302-309. DOI: 10.1002/jemt.20402

M.D. Ynsa, F.J. Ager, L.C. Alves, M.A. Zubeldia, J.C. Millan, T. Pinheiro, Elemental distributions in femoral bone of rat under osteoporosis preventive treatments. J. Microscopy 2006; 224:298-305.

PA Lopes, P Napoleão, T Pinheiro, F Ceia, JP Steghens, MC Santos, AM Viegas-Crespo. Systemic markers of the redox balance and apolipoprotein E polymorphism in atherosclerosis – the relevance for an integrated study. Biological Trace Element Research 2006;112: 57-76.

P. Napoleão, T. Pinheiro, C. Sousa Reis, Elemental characterisation of tissues of Octopus vulgaris along the Portuguese coast, Sc. Total Env., 2005;231:345-349.

P. Aguer, L.C. Alves, Ph. Barberet, E. Gontier, S. Incerti, C. Michelet-Habchi, Zs. Kertész, A.Z. Kiss, P. Moretto, J. Pallon, T. Pinheiro, J.E. Surlève-Bazeille, Z. Szikszai, A. Veríssimo, M.D. Ynsa, Skin morphology and layer identification using different STIM geometries, Nucl Instrum. and Meth. 2005;231:292-299.

M.C. Santos, A.L. Oliveira, A.M. Viegas-Crespo, L. Vicente, A. Barreiros, P. Monteiro, T. Pinheiro, A. Bugalho de Almeida, Systemic markers of redox balance in Chronic Obstrutive Pulmonary Disease, Biomarkers 2004;9:461-469.

A.M. Viegas-Crespo, P.A. Lopes, T. Pinheiro, M.C. Santos, P.D. Rodrigues, A.C. Nunes, C. Marques, M.L. Mathias, Hepatic elemental contents and SOD and GST activities in Algerian mice (Mus spretus) inhabiting a mine area at Central Portugal, The Science of Total Environ. 2003;311:101-109.29

T. Pinheiro, J.N. Silva, L.C. Alves, P. Filipe, Iron deposition in skin of patients with haemochromatosis, Nucl. Instr. and Meth. 2003;B210:373-377.

T. Pinheiro, L.C. Alves, F. Araújo, M.A. Barreiros, S. Bohic, A. Simionovici, Imaging and quantification of trace metals in biomedical samples using Synchrotron Induced X-ray Fluorescence and Nuclear Microprobe techniques, J. Phys. IV 2003;104:321-324.

M.A. Barreiros, T. Pinheiro, M.F. Araújo, M.M. Costa, M. Palha, R.C. da Silva, Quality assurance of X-ray spectrometry for chemical analysis, Spectrochim. Acta Part B, 2001;56:2095-2106.

P.A Lopes, T. Pinheiro, M.C. Santos, M.L. Mathias, M.J. Collares-Pereira, A.M. Viegas-Crespo, Response of antioxidant enzymes in freshwater fish populations (Leuciscus alburnoides complex) to inorganic pollutants exposure, The Science of Total Environ. 2001;280:153-163.

M.L. Carvalho, C. Casaca, J.P. Marques, T. Pinheiro, A.S. Cunha, P. Chevallier, Human teeth elemental profiles by synchrotron radiation: Dietary habits and environmental influence, X-ray Spectrom. 2001;30:190-193.

T. Pinheiro, L.C. Alves, A. Bugalho de Almeida, M.J. Palhano, E. Pålsgård, G.W. Grime, Airborne Particulate Matter Localisation in the Human Respiratory System, Nucl. Instr. and Meth. 1999;B158:499-504.

M.J. Almeida, G. Moura, T. Pinheiro, J. Machado, J. Coimbra, Modifications in Crassostrea gigas shell composition exposed to high concentrations of lead, Aquatic Toxicol. 1998;40:323-334

J. Canena, J. Reis, A.S. Pinto, A.M. Santos, J. Leitão, T. Pinheiro, M.G. Quina, Distribution of bismuth in the rat after oral dosing with ranitidine bismuth citrate and bismuth subcitrate, J. Pharm. and Pharmacol. 1998;50:279-283.

T. Pinheiro, A. Bugalho de Almeida, J.R. Vieira, A. Fernandes, L.C. Alves, M. Reis, J. Carvalho Soares, Elemental Distribution in the Human Respiratory System and Excretion Organs - Absorption and Accumulation, X-ray Spectrom. 1997;26:217-222.

J. Pallon, P. Homman, T. Pinheiro, M.J. Halpern, K. Malmqvist, A view on elemental distribution alterations of coronary artery walls in the atherogenesis, Nucl. Instr. and Methods B104(1995)344-350. doi:10.1016/0168-583X(95)00453-X