Membrane composition and structure. Mechanisms of pathogenicity in Candida species

13 novembro 2019, 09:00 • Miguel Nobre Parreira Cacho Teixeira

Membrane composition and structure: phospholipids, sphingolipids and sterols. Lipid rafts and eisosomes.

Mechanisms of pathogenicity in fungal pathogens of the Candida genus. Phenotypic switching, dimorphic growth, biofilm formation, excretion of proteases, lipases and phospholipases. Differences among the most common candida pathogens in the context of virulence mechanisms.

Stress response in eukaryotes (cont.)

11 novembro 2019, 09:00 • Miguel Nobre Parreira Cacho Teixeira

Autophagy. Apoptosis as mechanisms of stress response. Assymetric mitochondrial inheretance.

Stress response in eukaryotes

6 novembro 2019, 09:00 • Miguel Nobre Parreira Cacho Teixeira

The general stress response. Methods to detect oxidative stress and oxidative stress responsive mechanisms. Osmotic stress and Heat shock response.

Transporte de açucares em levedura

4 novembro 2019, 09:00 • Jorge Humberto Gomes Leitão

A aula foi leccionada pela Dra. Margarida Palma, que deu um seminário sobre o transporte de açucares em levedura, A Dra. Margarida abordou ainda as classes de transportadores e outros aspetos da bioquímica e fisiologia dos transportadores em levedura.

Multidrug resistance in eukaryotes (cont.)

30 outubro 2019, 09:00 • Miguel Nobre Parreira Cacho Teixeira

Role of new transporters of the Major Facilitator Superfamily (MFS) that confer multidrug resistance: from S. cerevisiae to fungal pathogens. Development and application of chemosensitizers as co-adjuvants in the administration of anticancer and antifungal agents.