Exploring the Human Genome

8 outubro 2012, 11:00 • Ana Teresa Correia de Freitas

Finding out about the Ensembl project.

Searching with a sequence using BLAT or BLAST.

Lab #2 DNA and Mutations

2 outubro 2012, 17:00 • Ana Teresa Correia de Freitas

In this lab we will explore these key questions:

·      How does DNA encode the characteristics of an organism?

·      In what different ways can mutations affect an organism?

·      How can a simple mutation end up having a major effect on the phenotype of an organism?

·      What does it mean to say that mutations are random?

Sequence alignment

2 outubro 2012, 12:30 • Ana Teresa Correia de Freitas

Scoring matrices

Dynamic Programming

Needleman-Wunsch algorithm

Smith-Waterman algorithm

Lab #2 DNA and Mutations

2 outubro 2012, 09:30 • Ana Teresa Correia de Freitas

In this lab we will explore these key questions:

·      How does DNA encode the characteristics of an organism?

·      In what different ways can mutations affect an organism?

·      How can a simple mutation end up having a major effect on the phenotype of an organism?

·      What does it mean to say that mutations are random?

Lab #2 DNA and Mutations

1 outubro 2012, 14:00 • Ana Teresa Correia de Freitas

In this lab we will explore these key questions:

·      How does DNA encode the characteristics of an organism?

·      In what different ways can mutations affect an organism?

·      How can a simple mutation end up having a major effect on the phenotype of an organism?

·      What does it mean to say that mutations are random?